Pemphigus Foliaceus of Sixteen Years’ Duration

Pemphigus Vulgaris and Pemphigus Foliaceus

The word “pemphigus” is derived from the Greek term "pemphix” meaning bubble or blister. Pemphigus is a group of autoimmune diseases (see Table 4) characterized by intra-epithelial blistering, resulting in superficial vesicles or bullae that easily rupture, resulting in ulceration of mucosal and/or cutaneous sites. Although rare, pemphigus causes significant morbidity and potential mortality fo...

Thymoma with pemphigus foliaceus.

A 75-year-old Japanese woman was referred to us because of an anterior mediastinal mass. Crusts and shallow erosions developed 10 months earlier on her upper chest, back, and scalp. Pemphigus foliaceus was diagnosed based on histological examination of skin biopsy specimens and positivity for serum anti-desmoglein 1 antibody by enzyme-linked immunosorbent assay. Neurological examination and ele...

Cutting Edge: Brazilian Pemphigus Foliaceus

Pemphigus herpetiformis with progression to pemphigus foliaceus: a case report.

Pemphigus herpetiformis (PH) is an uncommon variant of pemphigus that accounts for an estimated 6% to 7.2% of all cases of this skin disorder. The term pemphigus herpetiformis was coined by Jablonska et al. in 1975 to describe a entity that was clinically similar to dermatitis herpetiformis, showed acantholysis on biopsy, and responded to sulfapyridine. The authors considered that PH was a vari...

Treatment of pemphigus vulgaris and pemphigus foliaceus with mycophenolate mofetil.

BACKGROUND Mycophenolate mofetil is increasingly being used as a corticosteroid-sparing agent in immunosuppressive regimens. OBJECTIVE To elucidate the effectiveness of mycophenolate as adjuvant therapy in the treatment of both pemphigus vulgaris and pemphigus foliaceus. DESIGN Historical prospective study. SETTING University hospital. PATIENTS The study included 42 consecutive patients...